• M. Radovich, G. Jiang, B.A. Hancock, et al. “Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer: Preplanned Secondary Analysis of the BRE12-158 Randomized Clinical Trial,” JAMA Oncology, 2020. doi:10.1001/jamaoncol.2020.2295. PDF
  • R. Jain, S. Chittiboyina, C-L. Chang, S. Lelièvre, and C. A. Savran, “Deterministic culturing of single cells in 3D,” Scientific Reports 10, 10805, 2020. PDF
  • O. Gur, C-L. Chang, R. Jain, Y. Zhong, and C. A. Savran, “High-Purity isolation of rare singe cells from blood using a tiered microchip system,” PLoS ONE, 15(3): e0229949, 2020. PDF
  • C. Jung, J. Hawkins, S. K. Jones, Jr., Y. Xiao, J. R. Rybarski, K. E. Dillard, J. Hussmann, F. A. Saifuddin, C. A. Savran, A. D. Ellington, A. Ke, W. H. Press, and I. J. Finkelstein, “Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips,” Cell, vol. 170, pp. 35-47, 2017. PDF
  • W. Huang, C-L. Chang, N. D. Brault, O. Gur, Z. Wang, S. I. Jalal, P. S. Low, T. L. Ratliff, R. Pili and C. A. Savran, “Separation and dual detection of prostate cancer cells and protein biomarkers using a microchip device,” Lab On a Chip, vol. 17, no. 3, pp. 415-428, 2017. (Inside front cover of issue 3) PDF
  • H. Pajouhi, A.Y. Jou, R. Jain, A. Shakouri, C.A. Savran and S. Mohammadi, “Flexible complementary metal oxide semiconductor microelectrode arrays with applications in single cell characterization,” Applied Physics Letters, vol. 107, 203103, 2015. PDF
  • W. Huang, C-L. Chang, B-D. Chan, S.I. Jalal, D.E. Matei, P.S. Low and C.A. Savran, “Concurrent detection of cellular and molecular cancer markers using an immunomagnetic flow system,” Analytical Chemistry, vol. 87, no. 20, pp. 10161-10656, 2015. (Front cover of issue 20). PDF
  • H-H Wang, L. Wang, T.J. Jerde, B-D. Chan, C.A. Savran, G.N. Burcham, S. Crist and T.L. Ratliff, “Characterization of autoimmune inflammation induced prostate stem cell expansion,” The Prostate, vol. 75, no. 14, pp. 1620-1631, 2015. PDF
  • C-L. Chang, W. Huang, S.I. Jalal, B-D. Chan, A. Mahmood, S. Shahda, B.H. O’Neil, D.E. Matei and C.A. Savran, “Circulating tumor cell detection using a parallel flow micro-aperture chip system,” Lab On a Chip, vol. 15, no. 7, pp. 1677-1688, 2015. (Back cover of issue 7). PDF
  • B-D. Chan, K. Icoz, W. Huang, C-L. Chang, and C.A. Savran, “On-demand Weighing of Single Dry Biological Particles over a 5-order-of-magnitude Dynamic Range,” Lab On a Chip, vol. 14, no. 21, pp. 4188-4196, 2014. (Front cover of issue 21, Lab On a Chip 2014 “HOT Article”). PDF
  • C-L. Chang, S.I. Jalal, W. Huang, A. Mahmood, D.E. Matei and C.A. Savran, “High-Throughput Immunomagnetic Cell Detection Using a Microaperture Chip System,” IEEE Sensors Journal , vol. 14, no. 9, pp. 3008-3013, 2014. PDF
  • R.L. Gieseck, B-D. Chan, and C.A. Savran, “A humidity-sensitive hydrogel-Bacillus spore composite for micropatterning of bimolecular gradients,” Review of Scientific Instruments, 84,085003 2013. PDF
  • B-D. Chan, K. Icoz, R.L. Gieseck, and C.A. Savran, “Selective weighing of individual microparticles using a hybrid micromanipulator-nanomechanical resonator system,” IEEE Sensors Journal, vol. 13, no. 8, pp. 2857-2862, 2013. PDF
  • C-L. Chang, Z. Ding, V. Patchigolla, B. Ziaie and C.A. Savran, “Reflective Diffraction Gratings from Hydrogels as Biochemical Sensors,” IEEE Sensors Journal, vol. 12, no. 7, pp. 2374-2379, 2012. PDF
  • B-D. Chan, F. Mateen, C-L. Chang, K. Icoz, and C.A. Savran, “A Compact Manually Actuated Micromanipulator,” Journal of Microelectromechanical Systems, vol. 21, no. 1, pp. 7-9, 2012. PDF
  • G. Chitnis, Z. Ding, C-L. Chang, C.A. Savran and B. Ziaie, “Laser-treated hydrophobic paper: an inexpensive microfluidic platform”, Lab On a Chip, DOI: 10.1039/C0LC00512F, 2011. PDF
  • K. Icoz, and C.A. Savran, “Nanomechanical Biosensing with Immunomagnetic Separation”, Applied Physics Letters, vol. 97, 123701, 2010. PDF
  • J. Lee, K. Icoz, A. Roberts, A.D. Ellington and C.A. Savran, “Diffractometric Detection of Proteins Using Microbead-Based Rolling Circle Amplification”, Analytical Chemistry, vol. 82, no 1, pp. 197-202, 2010. PDF
  • T.J. Lee, H. Zhang, C-L. Chang, C.A. Savran, and P. Guo “Engineering of the Fluorescent-Energy-Conversion Arm of Phi29 DNA Packaging Motor for Single-Molecule Studies”, Small, vol. 5, no 21, pp. 2453-2459, 2009. PDF
  • C-L. Chang, H. Zhang, D. Shu, P. Guo, and C. A. Savran, “Bright-field analysis of phi29 DNA packaging motor using a magnetomechanical system”, Applied Physics Letters, vol. 93, pp. 153902, 2008.PDF | Supporting information
  • K. Icoz, B. D. Iverson, and C.A. Savran, “Noise analysis and sensitivity enhancement in immunomagnetic nanomechanical biosensors”, Applied Physics Letters, vol. 93, pp. 013902, 2008. PDF
  • J. Lee, J. Jang, D. Akin, C.A. Savran, R. Bashir, “Real-time detection of airborne viruses on a mass-sensitive device”, Applied Physics Letters, vol. 93, pp. 013901, 2008. PDF
  • G. Acharya, C-L. Chang, D. Holland, D.H. Thompson, C.A. Savran, “Rapid Detection of S-Adenosyl Homocysteine Using Self-Assembled Optical Diffraction Gratings”, Angewandte Chemie International Edition, vol 47, no 6, pp 1051-1053, 2008. PDF
  • G. Acharya, C-L. Chang, D.D. Doorneweerd, E. Vlashi, W.A. Henne, L.C. Hartmann, P.S. Low, C.A. Savran, “Immunomagnetic Diffractometry for diagnostic serum markers”, Journal of the American Chemical Society vol 129, pp 15824-9, 2007. PDF
  • C-L. Chang, G. Acharya and C.A. Savran, “In situ fabricated diffraction grating for biomolecular detection”, Applied Physics Letters, vol. 90, pp. 233901-3, 2007. PDF
  • G. Acharya, D.D. Doorneweerd, C-L. Chang, W.A. Henne, P.S Low and C.A. Savran, “Label-Free Optical Detection of Anthrax-Causing Spores”, Journal of American Chemical Society, vol. 129, no. 4, pp. 732 -733, 2007. PDF
  • S. M. Knudsen, J. Lee, A.D. Ellington and C.A. Savran, “Ribozyme-Mediated Signal Augmentation on a Mass-Sensitive Biosensor”, Journal of American Chemical Society, vol. 128, no. 50, pp. 15936-15937, 2006. PDF
  • W.A. Henne, D.D. Doorneweerd, J. Lee, P.S. Low and C.A. Savran, “Detection of Folate Binding Protein with Enhanced Sensitivity Using a Functionalized Quartz Crystal Microbalance Sensor”, Analytical Chemistry, vol. 78, no. 14, pp. 4880-4884, Jul. 2006 PDF
  • G. Acharya, C-L. Chang, C.A. Savran, “An optical biosensor for rapid and label-free detection of cells,” Journal of American Chemical Society, vol. 128, pp 3862-3863, March 2006. PDF
  • C.A. Savran, S.M. Knudsen, A.D. Ellington and S.R. Manalis, “Micromechanical detection of proteins using aptamer-based receptor molecules”, Analytical Chemistry, vol. 76, no. 11, pp. 3194-3198, Jul. 2004. PDF
  • C.A. Savran, T.P. Burg, J. Fritz, and S.R. Manalis, “Microfabricated mechanical biosensor with
    inherently differential readout,” Applied Physics Letters, vol. 83, no. 8, pp. 1659-1661, Aug. 2003. PDF
  • C.A. Savran, A.W. Sparks, J. Sihler, J. Li, W-C. Wu, D.E. Berlin, T.P. Burg, J. Fritz, M.A. Schmidt, S.R. Manalis, “Fabrication and Characterization of a micromechanical sensor for differential detection of nanoscale motions,” Journal of Microelectromechanical Systems, vol. 11, no. 6, pp. 703-708, Dec. 2002. PDF